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Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level

✍ Scribed by Betina Elfving; Henriette N. Buttenschøn; Leslie Foldager; Pia H.P. Poulsen; Johan H. Andersen; Matias B. Grynderup; Åse M. Hansen; Henrik A. Kolstad; Linda Kaerlev; Sigurd Mikkelsen; Jane F. Thomsen; Anders D. Børglum; Gregers Wegener; Ole Mors


Book ID
116691703
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
169 KB
Volume
46
Category
Article
ISSN
0022-3956

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Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that has antidepressant-like effects in animals and may be implicated in the etiology of mood-related phenotypes. However, genetic association studies of the BDNF Val66Met polymorphism (single nucleotide polymorphism rs6265) in major