## Abstract This study sought to establish a method of quantifying subjective perceptions of sleep against perceptions of lifeβquality and mood, using amended versions of the Pittsburgh sleep diary (PghSD) and quality of life of insomniacs (QOLI) questionnaire. Diaries and questionnaires were selfβ
Depression, sleep physiology, and antidepressant drugs
β Scribed by Andrew Winokur; Keith A. Gary; Shannon Rodner; Carole Rae-Red; Antonio T. Fernando; Martin P. Szuba
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 109 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1091-4269
- DOI
- 10.1002/da.1043
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Given the relationship between sleep and depression, there is inevitably going to be an effect of antidepressants on sleep. Current evidence suggests that this effect depends on the class of antidepressant used and the dosage. The extent of variation between the effects of antidepressan
The question of when antidepressant drugs (AD) initiate significant clinical actions in depressed patients is still unsettled. Findings from early studies on whether there is a lag in the onset of therapeutic actions were in disagreement. More recent results with the selective serotonin reuptake inh
The mechanism of action of the antidepressants was reviewed through the summer of 1995. Antagonism of monoamine transport is the primary cellular action associated with many antidepressant medications. However, an increased synaptic concentration of monoamines is not the actual mechanism of antidepr
## Abstract ## Background Disturbance of sleepβwake cycles is common in major depressive disorder (MDD), usually as insomnia, but also as hypersomnia or reduced daytime alertness. Agomelatine, an MT~1~ and MT~2~ receptor agonist and 5βHT~2C~ receptor antagonist, represents a novel approach in MDD,
## Abstract This study sought to investigate whether firstβdegree relatives of depressed patients report, and react to, sleep perceptions in the same way as the depressed group. Our previous research suggested that depressed individuals may experience greater sleep βdistressβ than healthy individua