Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease
β Scribed by Spencer Shaw; Kenneth P. Rubin; Charles S. Lieber
- Book ID
- 111949716
- Publisher
- Springer US
- Year
- 1983
- Tongue
- English
- Weight
- 389 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0163-2116
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Long-term ethanol feeding has been shown to selectively reduce hepatic mitochondrial glutathione content by impairing mitochondrial uptake of this thiol. In this study, we assessed the role of this defect in evolution of alcoholic liver disease by examining the mitochondrial glutathione pool and lip
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