## Abstract Human plasma fibronectin (Fn) is a large flexible protein stabilized by intermolecular ionic interactions forming a compact structure. On altering solution conditions, the structure can revert to a more expanded state, thereby exposing previously hidden domains (e.g., cellβbinding sites
Deposition of fibronectin on material surfaces exposed to plasma: Quantitative and biological studies
β Scribed by Frederick Grinnell; Trung V. Phan
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 875 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
β¦ Synopsis
Experiments were carried out to characterize plasma fibronectin deposition onto material surfaces exposed to plasma solutions. Under nonclotting conditions, the amount of fibronectin adsorption on the surfaces, determined by an indirect radioactive antibody assay, was maximal at low plasma concentrations (0.1 X). At higher concentrations of plasma, other plasma proteins ap-
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