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Deposition and passage of transthyretin through the blood-nerve barrier in recipients of familial amyloid polyneuropathy livers

✍ Scribed by Perdigoto, Rui; Tomé, Luís; Mota, Oscar; Negrão, Luís; B Geraldes, José; Furtado, Alexandre Linhares; Sousa, Mónica M; Ferrão, José; Fernandes, Rui; Guimarães, António

Book ID: 109885750
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 257 KB
Volume: 84
Category: Article
ISSN: 0023-6837
DOI: 10.1038/labinvest.3700107

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Transthyretin-derived amyloid deposition

Transthyretin-derived amyloid deposition on the gastric mucosa in domino recipients of familial amyloid polyneuropathy liver

✍ Yo-ichi Takei; Takahisa Gono; Masahide Yazaki; Shu-ichi Ikeda; Toshihiko Ikegami 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB 👁 1 views

Familial amyloid polyneuropathy (FAP) is a form of hereditary generalized amyloidosis. Liver tissue explanted from FAP patients has normal structure and function, except for the production of amyloidogenic variant transthyretin (TTR), and domino liver transplantation (DLT) using grafts from FAP pati