Depolarization of Cardiac Membrane Potential Promotes Calcium Waves
β Scribed by Sato, Daisuke; Bers, Donald M.
- Book ID
- 122458642
- Publisher
- Biophysical Society
- Year
- 2014
- Tongue
- English
- Weight
- 44 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0006-3495
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Rat brain astrocytes growing in primary monolayer cultures were swollen by exposing them to media of decreasing osmolality caused by removal of NaC1, and the effects of this treatment on their membrane potentials were measured by intracellular recording. Depolarizations were seen that were proportio
## Abstract The membrane potential is mainly maintained by the K^+^ concentration gradient across the cell membrane between the cytosol and the extracellular matrix. Here, we show that extracellular addition of highβmolecular weight hyaluronan depolarized the membrane potential of human fibroblasts