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Depletion of Nrf2 Enhances Inflammation Induced by Oxyhemoglobin in Cultured Mice Astrocytes

✍ Scribed by Hao Pan; Handong Wang; Lin Zhu; Lei Mao; Liang Qiao; Xingfen Su


Publisher
Springer
Year
2011
Tongue
English
Weight
482 KB
Volume
36
Category
Article
ISSN
0364-3190

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## Abstract Nitric oxide (NO) from astrocytes is one of the signalers used by the brain's extensive glial‐neuronal‐vascular network, but its excessive production by pro‐inflammatory cytokine‐stimulated glial cells can be cytodestructive. Here, we show how three pro‐inflammatory cytokines (IL‐1β, TN