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Depletion of mitochondrial DNA in the skeletal muscle of two cirrhotic patients with severe asthenia

โœ Scribed by Vito Pesce; Antonella Cormio; Lucia C. Marangi; Francesco W. Guglielmi; Angela M.S. Lezza; Antonio Francavilla; Palmiro Cantatore; Maria Nicola Gadaleta

Book ID
117520663
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
180 KB
Volume
286
Category
Article
ISSN
0378-1119

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Partial deficiency of complexes I and IV
Partial deficiency of complexes I and IV of the mitochondrial respiratory chain in skeletal muscle of two patients with mitochondrial myopathy
โœ J. Bleistein; S. Zierz ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 896 KB

Respiratory chain enzymes were studied in isolated mitochondria of two patients with mitochondrial myopathy. Both patients had been suffering from chronic progressive external ophthalmoplegia and abnormal muscular fatigability since late childhood. One of the patients exhibited the complete triad of