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Depletion of Ca2+ in the sarcoplasmic reticulum stimulates Ca2+ entry into mouse skeletal muscle fibres

✍ Scribed by Nagomi Kurebayashi; Yasuo Ogawa


Book ID
111119726
Publisher
Cambridge University Press
Year
2001
Tongue
English
Weight
262 KB
Volume
533
Category
Article
ISSN
0022-3751

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Regulation of Ca2+release from sarcoplas
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Ca2+ release from skeletal sarcoplasmic reticulum (SR) could be regulated by at least three mechanisms: 1) Ca2+, 2) calmodulin, and 3) Ca2+/calmodulin-dependent phosphorylation. Bell-shaped Ca(2+)-dependence of Ca2+ release from both actively- and passively-loaded SR vesicles suggest that opening an