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Dependence of RB+ uptake on regional flow and energetics in pig hearts: A 87RB AND 31P MR study

โœ Scribed by Valery Kupriyanov; Bo Xiang; Jiankang Sun; Olga Jilkina; Roxanne Deslauriers

Book ID
117141597
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
141 KB
Volume
33
Category
Article
ISSN
0022-2828

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Effects of flow and energy metabolism on
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## Abstract In this work the roles of coronary flow (CF) and metabolism in Rb^+^ (K^+^ congener) uptake were studied. In isolated pig hearts the left anterior descending artery (LAD) was cannulated to maintain adequate perfusion of the LAD bed. Rb^+^ loading was initiated and the LAD flow was eithe

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The effects of drugs that can modulate passive permeability of K(+) into cardiomyocytes in normal and reperfusion-damaged cardiac muscle were assessed. Rubidium ion (Rb(+)) was used as a K(+) tracer and (87)Rb-MRI as a detection method. The left anterior descending artery (LAD) of isolated pig heart

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The role of adrenergic stimulation in Rb(+) uptake in normal and ischemic areas of pig hearts was investigated using an agonist (dobutamine) and an antagonist (S-propranolol). The left anterior descending artery (LAD) in isolated pig hearts was cannulated to maintain adequate perfusion of the LAD be