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Dependence of Avidity on Linker Length for a Bivalent Ligand–Bivalent Receptor Model System

✍ Scribed by Mack, Eric T.; Snyder, Phillip W.; Perez-Castillejos, Raquel; Bilgiçer, Başar; Moustakas, Demetri T.; Butte, Manish J.; Whitesides, George M.

Book ID
120080083
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
678 KB
Volume
134
Category
Article
ISSN
0002-7863

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## Abstract Bivalent or polyvalent cooperative binding between ligand and receptor is much tighter and more efficient than monovalent binding of the same counterparts. Because of this, many biological processes involve polyvalent binding for realization of regulatory mechanisms. For this reason it