Deoxygenation of 1,4-epoxides by Grignard reagents
โ Scribed by David H. Blank; Gordon W. Gribble
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 198 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
Freshly prepared Grignard reagents in refluxing THF smoothly deoxygenate benzo-fused 1,4dihydro-1,4-epoxides to afford the corresponding naphthalenes and anthracenes in good yields.
๐ SIMILAR VOLUMES
Recent investigations have shown iron pentacarbonyl [Fe(CO)5] to be a useful reagent for effecting a variety of synthetic transformations.1 Non-polar solvents such as ethers have generally been employed for these reactions. In several cases, it has been demonstrated that reactions which do not take
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