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Deoxycytidine therapy in two patients with adenosine deaminase deficiency and severe immunodeficiency disease

✍ Scribed by Morton J. Cowan; Diane W. Wara; Arthur J. Ammann


Book ID
118374540
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
473 KB
Volume
37
Category
Article
ISSN
1090-2341

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Severe combined immunodeficiency disease
✍ Robertson Parkman; Erwin W Gelfand πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 English βš– 741 KB

Patients with severe combined immunodeficiency disease represent a model for the first clinical applications of gene therapy. Present attempts use insertion of the human adenosine deaminase gene into the peripheral blood T lymphocytes of patients who lack this gene. The ultimate treatment, however,