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Deoxycytidine kinase, thymidine kinase and cytidine deaminase and the formation of ARA-CTP in leukemic cells in different phases of the cell cycle

✍ Scribed by D.J. Richel; L.P. Colly; M.W. Arentsen-Honders; C.W.J. Starrenburg; R. Willemze

Book ID
113239262
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
572 KB
Volume
14
Category
Article
ISSN
0145-2126

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Formation of thymidine kinase and deoxyc
Formation of thymidine kinase and deoxycytidylate deaminase in synchronized cultures of chinese hamster cells temperature-sensitive for DNA synthesis
✍ Saul Kit; George N. Jorgensen πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 English βš– 501 KB

## Abstract Cytosol thymidine kinase (TK) and deoxycytidylate (dCMP) deaminase formation was investigated in synchronized cultures of K12 Chinese hamster cells which have a temperature‐sensitive lesion affecting the initiation of DNA synthesis. Enzyme formation was found to be cycloheximide‐sensiti