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Deoxycholic acid-induced signal transduction in HT-29 cells: Role of NF-κB and interleukin-8

✍ Scribed by Kim, Hyun-Soo; Lee, Dong Ki; Park, Sun Young; Baik, Soon Koo; Kwon, Sang Ok

Book ID
123157389
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
241 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Deoxycholic acid (DCA) has been implicated in colorectal carcinogenesis in humans with effects on proliferation and apoptosis, mediated at least in part by activation of transcription factors nuclear factor kappa B (NF‐κB), activator protein 1 (AP‐1) and protein kinase C (PKC) enzymes.