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Deoxyadenosine toxicity and cell cycle arrest in hydroxyurea-resistant S49 T-lymphoma cells

✍ Scribed by Daniel A. Albert; Edwardine Nodzenski

Book ID
115892291
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
840 KB
Volume
179
Category
Article
ISSN
0014-4827

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We investigated the cell cycle regulation of deoxyribonucleoside triphosphate (dNTP) metabolism in hydroxyurea-resistant (HYUR) murine S49 T-lymphoma cell lines. Cell lines 10-to 40-fold more hydroxyurea-resistant were selected in a stepwise manner. These HYUR cells exhibited increased CDP reductase

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