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Deoxy-nitrosugars 8th communication Convenient preparation of 1-C-nitroglycosyl chlorides. Halonitro ethers from hydroxy oximes

✍ Scribed by Roger Meuwly; Andrea Vasella


Publisher
John Wiley and Sons
Year
1984
Tongue
German
Weight
240 KB
Volume
67
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Partially protected 4‐ or 5‐hydroxy‐sugar oximes were transformed into 5‐ or 6‐membered 1‐C‐nitroglycosyl chlorides, respectively, by reaction with NaOCl under phase‐transfer conditions. With the exception of the oxidation of the gluco‐derivative 1 giving the anomers 6 and 7, the reactions were completely diastereoselective.