✍ Scribed by Fikrettin Şahin, Ayşegül Doğan, Selami Demirci (eds.)
No coin nor oath required. For personal study only.
This book explores Dental Stem Cell (DSC) biology, from a review of basic concepts for cell culture, to isolation, self-renewal, multipotency and differentiation, regulation by molecular medicine, and prospective research areas for regenerative medicine. The first seven chapters delve into basic DSC properties, vital signaling pathways involved in differentiation, pluripotency, iPS cell development from DSCs, and genetic engineering approaches of DSCs in accordance with the current literature. A comprehensive review of possible clinical applications and in vitro/in vivo studies follows, illustrating the future of DSC research for in the tissue engineering field. The text also discusses the political, ethical, social, and legal ramifications of the use of dental stem cells.
Expertly authored and drawing from a multitude of international perspectives, Dental Stem Cells is an invaluable addition to Springer’s Stem Cell Biology and Regenerative Medicine series. It is essential reading for advanced graduate students, basic researchers, and clinical investigators in the fields of stem cell therapy, biological sciences of dentistry, and regenerative medicine.
Front Matter....Pages i-xiii
Dental and Craniofacial Tissue Stem Cells: Sources and Tissue Engineering Applications....Pages 1-27
Immunomodulatory Properties of Stem Cells Derived from Dental Tissues....Pages 29-45
miRNA Regulation in Dental Stem Cells: From Development to Terminal Differentiation....Pages 47-67
Signaling Pathways in Dental Stem Cells During Their Maintenance and Differentiation....Pages 69-92
Genetically Engineered Dental Stem Cells for Regenerative Medicine....Pages 93-107
Dental Stem Cells vs. Other Mesenchymal Stem Cells: Their Pluripotency and Role in Regenerative Medicine....Pages 109-124
Induced Pluripotent Stem Cells Derived from Dental Stem Cells: A New Tool for Cellular Therapy....Pages 125-141
Dental Stem Cells in Oral, Maxillofacial and Craniofacial Regeneration....Pages 143-165
Dental Stem Cells: Possibility for Generation of a Bio-tooth....Pages 167-196
Dental Stem Cells for Bone Tissue Engineering....Pages 197-216
Dental Stem Cells: Their Potential in Neurogenesis and Angiogenesis....Pages 217-241
Dental Stem Cell Differentiation Toward Endodermal Cell Lineages: Approaches to Control Hepatocytes and Beta Cell Transformation....Pages 243-268
Dental Stem Cells in Regenerative Medicine: Clinical and Pre-clinical Attempts....Pages 269-287
Future Perspectives in Dental Stem Cell Engineering and the Ethical Considerations....Pages 289-307
Back Matter....Pages 309-317
Stem Cells; Regenerative Medicine/Tissue Engineering
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