Dengue haemorrhagic fever: Virus or host response?

✍ Scribed by Tikki Pang

• Book ID: 102760313
• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: English
• Weight: 527 KB
• Volume: 6
• Category: Article
• ISSN: 0265-9247
• DOI: 10.1002/bies.950060311

✦ Synopsis

The pathogenesis of dengue haemorrhagic fever has been the subject of intense research and considerable controversy. One hypothesisproposes that the immune response in a sensitized host is the primary mechanism. In contrast, others have suggested that the disease is caused by a more virulent, variant strain of dengue virus. Recent advances in molecular biology and hybridoma technology are providing valuable clues toward a solution and illustrating the fact that the course of a human viral disease is often a net result of unseparated interactions between host and virus.