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Dendritic α,ε-Poly(L-lysine)s as Delivery Agents for Antisense Oligonucleotides

✍ Scribed by Khee Dong Eom; Sun Mi Park; Huu Dung Tran; Myong Soo Kim; Ri Na Yu; Hoon Yoo

Publisher: Springer US
Year: 2007
Tongue: English
Weight: 755 KB
Volume: 24
Category: Article
ISSN: 0724-8741
DOI: 10.1007/s11095-006-9231-y

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## Abstract A new series of triblock [dendritic poly(L‐lysine)]‐__block__‐PLLA‐__block__‐[dendritic poly(L‐lysine)]s (DL~2~‐PLLA‐DL~2~) with PLLA block lengths of 11.5–26.5 and double 2‐generation PLL dendrons DL~2~ as model cationic amphiphiles were synthesized and characterized. Their CAC, self‐a