Dendritic spines, synaptic plasticity and neuronal survival: activity shapes dendritic spines to enhance neuronal viability

HDAC activity is required for BDNF to in

HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neurons

✍ Gaston Calfa; Christopher A. Chapleau; Susan Campbell; Takafumi Inoue; Sarah J. 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 421 KB

## Abstract Molecular mechanisms involved in the strengthening and formation of synapses include the activation and repression of specific genes or subsets of genes by epigenetic modifications that do not alter the genetic code itself. Chromatin modifications mediated by histone acetylation have be