𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dendritic polymer macromolecular carriers for drug delivery

✍ Scribed by Anil K Patri; István J Majoros; James R Baker Jr

Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
184 KB
Volume
6
Category
Article
ISSN
1367-5931

No coin nor oath required. For personal study only.

✦ Synopsis

Dendrimers are synthetic, highly branched, mono-disperse macromolecules of nanometer dimensions. Started in the mid-1980s, the research investigations into the synthetic methodology, physical and chemical properties of these macromolecules are increasing exponentially with growing interest in this field. Potential applications for dendrimers are now forthcoming. Properties associated with these dendrimers such as uniform size, water solubility, modifiable surface functionality and available internal cavities make them attractive for biological and drug-delivery applications.

📜 SIMILAR VOLUMES

Sequential polydepsipeptides as biodegra
Sequential polydepsipeptides as biodegradable carriers for drug delivery systems
✍ Yoshida, Masaru ;Asano, Masaharu ;Kumakura, Minoru ;Katakai, Ryoichi ;Mashimo, T 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 691 KB

## Abstract Sequential polydepsipeptides containing both peptide and ester bonds, poly[(L‐alanyl)~__n__~‐γ‐ethyl L‐glutamyl‐L‐lactyl] (__n__ = 0, 1, 2, and 3) (poly[(Ala)~__n__~‐Glu(OEt)‐Lac]), were prepared for application as biodegradable carriers for drug delivery systems. The __in vivo__ degrad

Swellable microparticles as carriers for
Swellable microparticles as carriers for sustained pulmonary drug delivery
✍ Ibrahim M. El-Sherbiny; Shayna McGill; Hugh D.C. Smyth 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 700 KB

In this investigation, novel biodegradable physically crosslinked hydrogel microparticles were developed and evaluated in vitro as potential carriers for sustained pulmonary drug delivery. To facilitate sustained release in the lungs, aerosols must first navigate past efficient aerodynamic filtering

Amphiphilic Comb-Like Polymers Based on
Amphiphilic Comb-Like Polymers Based on Poly(oxyethylene)s as Drug-Delivery Carriers
✍ Ki-Hyun Kim; Jong-Chan Lee; Jonghwi Lee 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB

## Abstract Comb‐like polymers with biocompatible oxyethylene backbones and amphiphilic side groups were synthesized via polymer‐analogous reactions. Using these polymers, indomethacin‐loaded polymeric micelles were fabricated with various drug‐to‐polymer weight ratios using the oil‐in‐water emulsi