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Dendritic cells: Intracellular trafficking, IRF7 and type-I-IFN responses

✍ Scribed by Bell, Elaine


Book ID
109954968
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
194 KB
Volume
5
Category
Article
ISSN
1474-1741

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Double-stranded secondary structures on
✍ M. Ceppi; N. Ruggli; V. Tache; H. Gerber; K. C. McCullough; A. Summerfield πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 985 KB

## Abstract ## Background The development of dendritic cell (DC)‐based vaccines using antigen‐encoding mRNA requires identification of the critical parameters for efficient __ex vivo__ loading of DCs. Exogenously delivered mRNA can induce DC activation, but the molecular mechanisms involved are un