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Dendritic cells induced in the presence of GM-CSF and IL-5

✍ Scribed by Huanfa Yi; Lianjun Zhang; Yu Zhen; Xiaoyan He; Yong Zhao

Book ID
116397834
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
1014 KB
Volume
37
Category
Article
ISSN
1043-4666

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The AML14.3D10 human myeloid leukemic cell line expresses receptors for granulocytemacrophage colony stimulating factor (GM-CSF) and interleukin-5 (IL-5), but not IL-3. We have found that this cell line produces GM-CSF in amounts up to 113 pg/ml in culture supernatants. Deprivation of endogenous GM-