Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules

Cytokine production by dendritic cells g

Cytokine production by dendritic cells genetically engineered to express IL-4: induction of Th2 responses and differential regulation of IL-12 and IL-23 synthesis

✍ Yoshitaka Morita; Raj Gupta; Kelly M. Seidl; Kevin T. McDonagh; David A. Fox 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 173 KB 👁 1 views

## Abstract Dendritic cells (DCs) retrovirally transduced with IL‐4 have recently been shown to inhibit murine collagen‐induced arthritis and associated Th1 immune responses __in vivo__, but the mechanisms that underly these effects are not yet understood. In this report we demonstrate that IL‐4‐tr