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Dendritic Cells and Antigen Presentation in the Regulation of Cytotoxic T Lymphocyte Responses against Viruses and Transplantation Antigens

✍ Scribed by CORNELIS J. M. MELIEF; CLAIRE J. P. BOOG; WIES L. E. VASMEL; JOLANDE BOES; ARIE C. VOORDOUW; W. MARTIN KAST

Book ID
119861891
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
674 KB
Volume
532
Category
Article
ISSN
0890-6564

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## Abstract Cytotoxic T lymphocytes (CTL) recognize antigenic peptides presented by major histocompatibility complex class I (MHC‐I) molecules on the surface of target cells. Optimal induction of CD8^+^ CTL depends on the amount of relevant peptide/MHC‐I complexes and the presence of co‐stimulatory