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Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study

✍ Scribed by Christian Bauer; Marc Dauer; Samira Saraj; Maximilian Schnurr; Franz Bauernfeind; Alexander Sterzik; Jana Junkmann; Veronika Jakl; Rosemarie Kiefl; Fuat Oduncu; Bertold Emmerich; Doris Mayr; Thomas Mussack; Christiane Bruns; Dominik Rüttinger; Claudius Conrad; Karl-Walter Jauch; Stefan Endres; Andreas Eigler


Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
388 KB
Volume
60
Category
Article
ISSN
0340-7004

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In a pilot phase 1/11 study we have tested synthetic ras peptides used as a cancer vaccine in 5 patients with advanced pancreatic carcinoma. The treatment principle used was based on loading professional antigen-presenting cells (APCs) from peripheral blood with a synthetic ras peptide corresponding