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Dendritic calcium channels and hippocampal long-term depression

✍ Scribed by Brian R. Christie; Jeffrey C. Magee; Daniel Johnston

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 947 KB
Volume: 6
Category: Article
ISSN: 1050-9631
DOI: 10.1002/(sici)1098-1063(1996)6:1<17::aid-hipo4>3.0.co;2-4

No coin nor oath required. For personal study only.

✦ Synopsis

The authors examine the potential role of the different sources of dendritic Ca2+ influx in long-term depression (LTD) of synaptic efficacy. Recent data on the location and functional distribution of voltage-gated Ca2+ channels obtained from fluorescence imaging and patch clamp experiments are presented. This is followed by a discussion of the existing evidence for different sources of Ca2+ playing a role in the induction of LTD. The authors conclude that a number of key issues

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