Second Edition. - Oxford University Press, 2008. - 550 p.
A long-awaited new edition of a successful and influential volume
The only book dedicated to this topic, with chapters from leading experts and laboratories
Chapters progress from the morphology, evolution, and development of dendrites, to their unique properties and function, as well as their role in plasticity and disease, thus providing a logical and comprehensive flow of information on the topic
New to this edition
Includes 5 completely new chapters
Now with full colour illustrations
Dendrites form the major receiving part of neurons. It is within these highly complex, branching structures that the real work of the nervous system takes place. The dendrites of neurons receive thousands of synaptic inputs from other neurons. However, dendrites do more than simply collect and funnel these signals to the soma and axon; they shape and integrate the inputs in complex ways. Despite being discovered over a century ago, dendrites received little research attention until the early 1950s. Over the past few years there has been a dramatic explosion of interest in the function of these beautiful structures. Recent new research has developed our understanding of the properties of dendrites, and their role in neuronal function.
The first edition of Dendrites was a landmark in the literature, stimulating and guiding further research. The new edition substantially updates the earlier volume, and includes 5 new chapters and colour illustrations. Its gathers new information on dendrites into a single volume, with contributions written by leading researchers in the field. It presents a survey of the current state of our knowledge of dendrites, from their morphology and development through to their electrical, chemical, and computational properties. As such it will not only be of interest to researchers and graduate-level students in neuroscience, but will also be useful to researchers in computer science and IT, psychology, physiology, and biophysics.
Readership: Neuroscientists, researchers in computer science and IT, psychology, physiology, and biophysics
John C Fiala, Josef Spacek & Kristen M Harris: Dendrite structure
Gayle M Wittenberg & Samuel S-H Wang: Evolution and scaling of dendrites
Hollis T Cline, Jorge Santos da Silva & Jennifer Bestman: Dendrite development
Franck Polleux & Anirvan Ghosh: Molecular determinants of dendrite and spine development
Lindy Barrett & James Eberwine: RNA targeting, trafficking and translation in dendrites: contribution to synaptic tagging and plasticity
Dane Chetkovich & Roger Nicoll: Organization and regulation of the post-synaptic density
Zoltan Nusser: Subcellular distribution of neurotransmitter receptors and voltage-gated ion channels
R Angus Silver & Mark Farrant: Neurotransmitter-gated ion channels in dendrites
Jeffrey C Magee: Dendritic voltage-gated ion channels
Fritjof Helmchen: Biochemical compartmentalization in dendrites
Adam Carter & Bernardo Sabatini: Spine calcium signaling
Wilfrid Rall: An historical perspective on modeling dendrites
Ithai Rabinowitch, Michael London & Idan Segev: A theoretical view of the neuron as an input-output plastic device
Nelson Spruston, Greg Stuart & Michael Hausser: Dendritic integration
Troy Margrie & Nathan Urban: Dendrites as transmitters
Bartlett W Mel: Why have dendrites? A computational perspective
Gilles Laurent & Alexander Borst: Short stories about small brains: linking biophysics to computation
Zachary F Mainen & Larry Abbott: Functional plasticity at dendritic synapses
Anna Dunaevsky & Catherine S Woolley: Structural plasticity of dendrites
Christophe Bernard, Mala Shah & Daniel Johnston: Dendrites and disease
Michael Hausser, Nelson Spruston & Greg Stuart: Conclusion: the future of dendrites