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Dendrimer Nanocomposites as New Generation X-ray Contrast Agents

✍ Scribed by T. Ould Ely; Manju Sharma; Wojciech G. Lesniak; Vladimir A. Sinani; Barbara Foster; Lajos P. Balogh

Book ID
108217003
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
46 KB
Volume
3
Category
Article
ISSN
1549-9634

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## Abstract Macromolecules conjugated with polyethylene glycol (PEG) acquire more hydrophilicity, resulting in a longer half‐life in circulation and lower immunogenicity. Two novel conjugates for MRI contrast agents were synthesized from a generation‐4 polyamidoamine dendrimer (G4D), 2‐(__p__‐isoth