Demyelination occurring during anti–tumor necrosis factor α therapy for inflammatory arthritides
✍ Scribed by Niveditha Mohan; Evelyne T. Edwards; Thomas R. Cupps; Patrick J. Oliverio; Glenn Sandberg; Heidi Crayton; John R. Richert; Jeffrey N. Siegel
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 611 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0004-3591
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The conventional treatment of inflammatory bowel disease (IBD) has focused on nonspecifically targeting mucosal inflammation. In the last decade, with the advent of novel biological agents that directly inhibit proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-a), rapid progress ha
## Abstract ## Objective Ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) are clinically and pathologically linked. Anti–tumor necrosis factor (anti‐TNF) agents are efficacious in treating AS, but not all are equally effective in treating IBD (Crohn's disease [CD] and ulcerative co