High proportions of mtDNA duplications i
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Fromenty, Bernard; Carrozzo, Rosalba; Shanske, Sara; Schon, Eric A.
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Article
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1997
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John Wiley and Sons
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English
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Kearns-Sayre syndrome (KSS) is a sporadic multisystem mitochondrial disorder characterized by progressive external ophthalmoplegia, pigmentary retinopathy, onset before age 20, and severe cardiac conduction defects that can lead to death. KSS patients harbor partial deletions of mitochondrial DNA (โฌ