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Demonstration of Y/autosomal translocations using distamycin A

✍ Scribed by M. Schmid

Publisher
Springer
Year
1979
Tongue
English
Weight
436 KB
Volume
53
Category
Article
ISSN
0340-6717

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✦ Synopsis

The condensation of the brightly fluorescing Y-heterochromatin is prevented by cultivating leukocytes in a medium containing distamycin A. This technique provides a reliable method for the identification of those Y/autosomal translocations in which Y heterochromatin is involved. A case of a familiar Y/22 translocation and the distamycin A technique are described.

πŸ“œ SIMILAR VOLUMES

An azoospermic male with a Y/Autosome tr
An azoospermic male with a Y/Autosome translocation
✍ I. Lopez Pajares; A. Delicado; P. V. Cobos; F. Sanchez Corral; C. Cuadrado πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 201 KB

This report describes an azoospermic male carrying a Y/autosome translocation. The patient had a 46,X,t(Y;10)(q12;p13) chromosome complement in a lymphocyte culture. The cytogenetic study of this patient is described, together with testicular histology, spermiogram, hormone levels, and clinical hist