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Demonstration of the distribution of Coxsackie virus RNA in neonatal mice by non-isotopic in situ hybridization

✍ Scribed by David A. Hilton; Carol Day; James H. Pringle; Alan Fletcher; Sharon Chambers


Book ID
119115154
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
888 KB
Volume
40
Category
Article
ISSN
0166-0934

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## Abstract The pathology of Coxsackie virus B4 (CVB4) infection in a murine model was investigated by in situ hybridization using a biotinylated cDNA probe derived from CVB4. During the acute phase of infection virus RNA sequences were detected in the exocrine pancreas of 60% of mice infected with