We report here the first demonstration in normal, as opposed to chimaeric mice, of the clonal architecture of the small intestine, oesophagus, breast, and thyroid, using polymorphism of the X-linked enzyme glucose-6-phosphate dehydrogenase (G6PD, EC 1.1.1.49) as a clonal marker. Reproducible results
β¦ LIBER β¦
Demonstration of somatic mutation and colonic crypt clonality by X-linked enzyme histochemistry
β Scribed by Griffiths, D. F. R.; Davies, S. J.; Williams, D.; Williams, G. T.; Williams, E. D.
- Book ID
- 109754412
- Publisher
- Nature Publishing Group
- Year
- 1988
- Tongue
- English
- Weight
- 506 KB
- Volume
- 333
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/333461a0
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