## Abstract Few diseases have had such a profound influence on human evolution and history as malaria. Despite intense efforts malaria infection continues to be a major killer. The causative agent of malaria, the unicellular eukaryote __Plasmodium__, displays a fascinating biology in which ubiquito
Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites
β Scribed by Moriya Tsuji; Denise Mattei; Ruth S. Nussenzweig; Daniel Eichinger; Fidel Zavala
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 832 KB
- Volume
- 80
- Category
- Article
- ISSN
- 1432-1955
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π SIMILAR VOLUMES
Heat shock proteins (HSPs) are a family of polypeptides which are induced in response to diverse forms of cell injury including hyperthermia, anoxia, ethanol, heavy metals, and others, with a presumably protective function. Among several species of HSPs, the 70 kD protein (HSP70) is the most abundan
The 70kDa heat-shock protein (HSP70) is conserved across prokaryotes and eukaryotes, and the protein as well as its encoding gene have been applied in phylogenetic studies of different parasites. In spite of the frequent use of New World Leishmania species identification on the basis of restriction