Demonstration of common specific antigen(s) in mouse and hamster polyoma tumors
✍ Scribed by I. Hellström; H. O. Sjögren
- Publisher
- John Wiley and Sons
- Year
- 1966
- Tongue
- French
- Weight
- 473 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
A specific, non-virion antigen common to mouse and hamster polyoma tumor cells was detected by the colony inhibition (CI) technique. This antigen was not readily detectable by transplantation methods. ' Serum titers were determined according to the HI technique of Eddy ct ul., (1958). * Undiluted serum had no virus-neutralizing activity. ' SFS 57A is a non-clonal polyoma tumor which origina'ed in an (A x C57BL)F, mouse. Titers up to I :lo0 were considered to depend o n non-specific inhibition (Sjogren, 1964) and titers 1:ZoO or more clearly positive. SEWA-CIO is a non-virus-releasing clone of the polyoma tumor SEWA (of A.SW genotype).
YLD is a Moloney leukemia of C57 leaden origin.
* The D, dose stands for the minimum cell doses which in pilot experiments grew in 100% of untreated recipients.