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Demonstration of clonality in neutrophils using FISH in a case of chronic neutrophilic leukemia

✍ Scribed by Froberg, M K; Brunning, R D; Dorion, P; Litz, C E; Torlakovic, E

Book ID
110053767
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
637 KB
Volume
12
Category
Article
ISSN
0887-6924

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✍ Matano, Sadaya; Nakamura, Shinobu; Kobayashi, Kazumi; Yoshida, Takashi; Matsuda, πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 89 KB πŸ‘ 3 views

We encountered a 67-year-old female with chronic neutrophilic leukemia (CNL). Cytogenetic study showed she had a deletion in the long arm of chromosome 20. This finding indicates that CNL, in this case, is a clonal disorder. Most CNL patients have normal karyotypes, and only four patients with cytog