Demonstration of both β1- and β2-adrenoceptors mediating negative chronotropic effects on spontaneous activity in isolated bovine mesenteric lymphatics

Opposite effects of α1- and β-adrenocept

Opposite effects of α1- and β-adrenoceptor stimulation on both glutamate- and γ-aminobutyric acid-mediated spontaneous transmission in cultured rat hippocampal neurons

✍ Ariane Croce; Hélène Astier; Max Récasens; Michel Vignes 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 422 KB

## Abstract The effects of adrenergic receptor stimulation on spontaneous synaptic transmission were investigated in cultured rat hippocampal neurons by recording spontaneous excitatory and inhibitory postsynaptic currents (sEPSC and sIPSC). Noradrenaline (NA) inhibited sEPSC in a concentration‐dep