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Demonstration of antibodies binding to autologous and allogeneic leukemic cells in childhood ALL

✍ Scribed by F�ldt, R. ;Ankerst, J. ;Garwicz, S.


Book ID
104721433
Publisher
Springer-Verlag
Year
1986
Weight
407 KB
Volume
52
Category
Article
ISSN
1432-0584

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Bispecific CD3xCD19 antibodies and CD28 co-stimulating antibodies were used to activate T cells in bone marrow aspirates (n ‫؍‬ 8) of children with B cell-derived acute lymphoblastic leukemia. Bone marrow specimens were incubated for 10 days with CD3xCD19 bispecific and CD28 antibodies. Changes in t