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Demonstration of a monovalent cation-selective channel in a sub-population of human platelet intracellular membranes

✍ Scribed by S Diane Manning; Neville Crawford; Alan J Williams

Book ID
115981835
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
106 KB
Volume
22
Category
Article
ISSN
0022-2828

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Endothelial cells obtained from human umbilical chord have been studied by the patch clamp method. An ion channel is described that is activated by microM concentrations of histamine and shows a slow run-down in cell-attached patches. After excision, channel activity quickly runs down to zero open p