Demonstration of a catecholaminergic innervation in human perirenal brown adipose tissue at various ages in the adult

Quantitative allele-specific PCR: Demons

Quantitative allele-specific PCR: Demonstration of age-associated accumulation in human tissues of the A→G mutation at nucleotide 3243 in mitochondrial DNA

✍ Vincent W. S. Liu; Chunfang Zhang; Anthony W. Linnane; Phillip Nagley 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 2 views

We have developed an improved allele-specific polymerase chain reaction (AS-PCR) procedure that can selectively amplify mutant DNA sequences (which differ from the normal sequences by a single base pair) in the presence of large excess of normal sequences. We applied this procedure to quantification