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Dementia of the Alzheimer type and hypothalamus-pituitary-adrenocortical axis: changes in cerebrospinal fluid corticotropin releasing factor and plasma cortisol levels

โœ Scribed by E. Martignoni; F. Petraglia; A. Costa; G. Bono; A. R. Genazzani; G. Nappi


Book ID
114783161
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
501 KB
Volume
81
Category
Article
ISSN
0001-6314

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Cerebrospinal fluid corticotropin-releas
โœ Emilia Martignoni; Alfredo Costa; Giuseppe Nappi; Felice Petraglia; Anna Monzani ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 376 KB

Experimental findings have recently suggested a toxic role for glucocorticoids in hippocampus, the main brain target for the adrenocortical hormones. In this study, we explored the activity of the hypothalamuspituitary-adrenal (HPA) axis in a group of patients with dementia of the Alzheimer's type (