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Dementia in Huntington's disease is associated with neurochemical deficits in the caudate nucleus, not the cerebral cortex

✍ Scribed by Reynolds, Gavin P.; Pearson, Sally J.; Heathfield, Kenneth W.G.


Book ID
122593842
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
344 KB
Volume
113
Category
Article
ISSN
0304-3940

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## Abstract Huntington's disease is a dominantly inherited, progressive neurodegenerative disorder causing marked pathology in the basal ganglia. The pathophysiology of the selective neuronal death in as yet unknown, but evidence suggests that the neurotoxicity may result from endogenous substances