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Deltorphin II enhances extracellular levels of dopamine in the nucleus accumbens via opioid receptor-independent mechanisms

✍ Scribed by Kaoru Murakawa; Noriya Hirose; Koji Takada; Tsutomu Suzuki; Hiroshi Nagase; Alexander R. Cools; Noriaki Koshikawa

Book ID
113584654
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
173 KB
Volume
491
Category
Article
ISSN
0014-2999

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Repeated administration of the selective
Repeated administration of the selective kappa-opioid receptor agonist U-69593 increases stimulated dopamine extracellular levels in the rat nucleus accumbens
✍ JosΓ© Antonio Fuentealba; Katia Gysling; Karin Magendzo; MarΓ­a Estela AndrΓ©s πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 244 KB

Reinforcing properties of drugs of abuse are reduced by the coadministration of kappa opioid receptor (KOR) agonists. This effect is related to the inhibition of dopamine (DA) release in the nucleus accumbens (NAc) produced by the acute administration of KOR agonists. The present study was undertake