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Delivery of Therapeutic Agents Through Intracerebroventricular (ICV) and Intravenous (IV) Injection in Mice

✍ Scribed by Glascock, Jacqueline J.; Osman, Erkan Y.; Coady, Tristan H.; Rose, Ferrill F.; Shababi, Monir; Lorson, Christian L.


Book ID
118029948
Publisher
MyJoVE Corporation
Year
2011
Tongue
English
Weight
256 KB
Volume
56
Category
Article
ISSN
1940-087X

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## Abstract ## Objective Glomerular mesangial cells are active participants in the pathogenesis of lupus glomerulonephritis (GN). Thus, targeted delivery of therapeutic agents to mesangial cells would be an attractive approach to treatment. However, lack of known unique mesangial cell surface mark