Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
β Scribed by Alvarez-Erviti, Lydia; Seow, Yiqi; Yin, HaiFang; Betts, Corinne; Lakhal, Samira; Wood, Matthew J A
- Book ID
- 109900822
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 668 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1087-0156
- DOI
- 10.1038/nbt.1807
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract The largest obstacle to the effective use of short interfering RNA (siRNA) in an animal body is the ability to deliver it to the target tissue. Here we showed a systemic delivery method of siRNA specific to pregrown solid tumors __via__ atelocollagen. Atelocollagen facilitated the selec