## Abstract Cross‐presentation is the key process in stimulation of cytotoxic T lymphocyte (CTL) immune response in eliminating many infectious diseases and tumors. Previous studies have shown that surface modification of poly(D,L‐lactic‐__co__‐glycolic acid) (PLGA) particles with polycations enhan
Delivery of a peptide via poly(d,l-lactic-co-glycolic) acid nanoparticles enhances its dendritic cell–stimulatory capacity
✍ Scribed by Corbin Clawson; Chien-Tze Huang; Diahnn Futalan; Daniel Martin Seible; Rebecca Saenz; Marie Larsson; Wenxue Ma; Boris Minev; Fiona Zhang; Mihri Ozkan; Cengiz Ozkan; Sadik Esener; Davorka Messmer
- Book ID
- 104063119
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 941 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1549-9634
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## Abstract The purpose of this research was to investigate the use of biodegradable poly(D,L‐lactic‐__co__‐glycolic acid) nanoparticles (PLGA‐NP) as a vaccine delivery system to codeliver antigen, ovalbumin (OVA) along with monophosphoryl lipid A (MPLA) as adjuvant for induction of potent CD4^+^ a