Delirium during heroin withdrawal with doxepin: A short report
✍ Scribed by Yoram Barak; Joseph Levine; Yair Lampl; Avner Elizur
- Book ID
- 102261170
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 279 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0885-6222
No coin nor oath required. For personal study only.
✦ Synopsis
Doxepin was evaluated in a group of 10 patients for its efficacy in decreasing withdrawal symptoms during ambulatory heroin withdrawal. Although no subjective relief was reported by the subjects, during the 10 days trial, four of the patients developed full blown delirium during the trial's first three days. Since delirium is rarely one of the complications of heroin withdrawal the question whether doxepin enhanced or induced its appearance in these patients, remains unanswered.
Until this issue is resolved we suggest cessation of doxepin usage in the initial withdrawal phase from heroin. KEY WORDS-heroin withdrawal; doxepin; deIirium 'base line'. Results are average for the group. Range of H.R. in our study was 57-81. Range of systolic B.P. in our study was 95-120. Range of diastolic B.P. in our study was 75-100.