Activation of the intrinsic and extrinsi
โ
Takeo Yamaguchi; Kenji Hashiguchi; Satoshi Katsuki; Wakako Iwamoto; Shoichiro Ts
๐
Article
๐
2008
๐
SP Versita
๐
English
โ 466 KB
## Abstract We previously demonstrated that caspase-3, an executioner of apoptosis, is activated in the pressure-induced apoptosis of murine erythroleukemia (MEL) cells (at 100 MPa). Here, we examined the pathway of caspase-3 activation using peptide substrates and caspase inhibitors. Using the sub